3UOB
Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-deoxy-2'-beta-fluoro-cytidine
Summary for 3UOB
Entry DOI | 10.2210/pdb3uob/pdb |
Related | 3UO7 |
Descriptor | 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1FC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase (3 entities in total) |
Functional Keywords | dsdna, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q13569 |
Total number of polymer chains | 4 |
Total formula weight | 59727.72 |
Authors | |
Primary citation | Zhang, L.,Lu, X.,Lu, J.,Liang, H.,Dai, Q.,Xu, G.L.,Luo, C.,Jiang, H.,He, C. Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat.Chem.Biol., 8:328-330, 2012 Cited by PubMed: 22327402DOI: 10.1038/nchembio.914 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.011 Å) |
Structure validation
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