3ULS

Crystal structure of Fab12

Summary for 3ULS

Entry DOI	10.2210/pdb3uls/pdb
Related	3ULU 3ULV
Descriptor	Fab12 light chain, Fab12 heavy chain (3 entities in total)
Functional Keywords	toll-like receptor-3, tlr3, innate immunity, immunoglobulin, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	94616.62
Authors	Luo, J.,Gilliland, G.L.,Obmolova, O.,Malia, T.,Teplyakov, A. (deposition date: 2011-11-11, release date: 2012-05-23, Last modification date: 2023-09-13)
Primary citation	Luo, J.,Obmolova, G.,Malia, T.J.,Wu, S.J.,Duffy, K.E.,Marion, J.D.,Bell, J.K.,Ge, P.,Zhou, Z.H.,Teplyakov, A.,Zhao, Y.,Lamb, R.J.,Jordan, J.L.,San Mateo, L.R.,Sweet, R.W.,Gilliland, G.L. Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421:112-124, 2012 Cited by PubMed: 22579623 DOI: 10.1016/j.jmb.2012.05.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.495 Å)

Structure validation