3UKE

(S)-cMOE-BNA decamer structure

Summary for 3UKE

• Entry DOI: 10.2210/pdb3uke/pdb
• Related: 3UKB 3UKC
• Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*(CSM)P*AP*CP*GP*C)-3') (2 entities in total)
• Functional Keywords: a-form dna, bicyclic nucleic acid, bna, dna, c-moe-bna, antisense oligonucleotides
• Total number of polymer chains: 2
• Total formula weight: 6206.08

Authors

Pallan, P.S.,Egli, M. (deposition date: 2011-11-09, release date: 2012-06-20, Last modification date: 2023-09-13)

• Primary citation: Pallan, P.S.,Allerson, C.R.,Berdeja, A.,Seth, P.P.,Swayze, E.E.,Prakash, T.P.,Egli, M.; Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs.; Chem.Commun.(Camb.), 48:8195-8197, 2012; PubMed: 22614180; DOI: 10.1039/c2cc32286b

Experimental method

X-RAY DIFFRACTION (1.68 Å)