3UI2

Crystal structure of the cpSRP54 tail bound to cpSRP43

3UI2 の概要

• エントリーDOI: 10.2210/pdb3ui2/pdb
• 関連するPDBエントリー: 3deo 3dep
• 分子名称: Signal recognition particle 43 kDa protein, chloroplastic, Signal recognition particle 54 kDa protein, chloroplastic (2 entities in total)
• 機能のキーワード: ankyrin repeat, chromodomain, aromatic cage, signal recognition particle, protein targeting, membrane protein chaperone, chloroplast, transport protein
• 由来する生物種: Arabidopsis thaliana (mouse-ear cress,thale-cress); 詳細
• 細胞内の位置: Plastid, chloroplast stroma: O22265 P37107
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28337.81

構造登録者

Holdermann, I.,Wild, K.,Sinning, I. (登録日: 2011-11-04, 公開日: 2012-01-11, 最終更新日: 2023-09-13)

主引用文献

Holdermann, I.,Meyer, N.H.,Round, A.,Wild, K.,Sattler, M.,Sinning, I.
Chromodomains read the arginine code of post-translational targeting.
Nat.Struct.Mol.Biol., 19:260-263, 2012

PubMed Abstract: Chromodomains typically recruit protein complexes to chromatin and read the epigenetic histone code by recognizing lysine methylation in histone tails. We report the crystal structure of the chloroplast signal recognition particle (cpSRP) core from Arabidopsis thaliana, with the cpSRP54 tail comprising an arginine-rich motif bound to the second chromodomain of cpSRP43. A twinned aromatic cage reads out two neighboring nonmethylated arginines and adapts chromodomains to a non-nuclear function in post-translational targeting.

PubMed: 22231402
DOI: 10.1038/nsmb.2196

実験手法

X-RAY DIFFRACTION (3.178 Å)