3UEK

Crystal structure of the catalytic domain of rat poly (ADP-ribose) glycohydrolase

Summary for 3UEK

• Entry DOI: 10.2210/pdb3uek/pdb
• Related: 3UEL
• Descriptor: Poly(ADP-ribose) glycohydrolase (2 entities in total)
• Functional Keywords: mammalian parg, macrodomain, hydrolase
• Biological source: Rattus norvegicus (brown rat,rat,rats)
• Cellular location: Nucleus (By similarity): Q9QYM2
• Total number of polymer chains: 1
• Total formula weight: 67780.16

Authors

Kim, I.K.,Kiefer, J.R.,Stegemann, R.A.,Classen, S.,Tainer, J.A.,Ellenberger, T. (deposition date: 2011-10-30, release date: 2012-05-23, Last modification date: 2024-02-28)

• Primary citation: Kim, I.K.,Kiefer, J.R.,Ho, C.M.,Stegeman, R.A.,Classen, S.,Tainer, J.A.,Ellenberger, T.; Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element.; Nat.Struct.Mol.Biol., 19:653-656, 2012; PubMed: 22609859; DOI: 10.1038/nsmb.2305

Experimental method

X-RAY DIFFRACTION (1.95 Å)