3UBB

The crystal structure of GlpG in complex with a phosphonofluoridate inhibitor

3UBB の概要

• エントリーDOI: 10.2210/pdb3ubb/pdb
• 分子名称: Rhomboid protease glpG, propan-2-yl hydrogen (S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl]phosphonate (3 entities in total)
• 機能のキーワード: helix bundle, membrane, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20829.59

構造登録者

Xue, Y.,Ha, Y. (登録日: 2011-10-24, 公開日: 2012-06-13, 最終更新日: 2019-07-17)

• 主引用文献: Xue, Y.,Chowdhury, S.,Liu, X.,Akiyama, Y.,Ellman, J.,Ha, Y.; Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S' Subsites.; Biochemistry, 51:3723-3731, 2012; PubMed: 22515733; DOI: 10.1021/bi300368b

実験手法

X-RAY DIFFRACTION (2.601 Å)