3UA3

Crystal Structure of Protein Arginine Methyltransferase PRMT5 in complex with SAH

Summary for 3UA3

• Entry DOI: 10.2210/pdb3ua3/pdb
• Related: 3UA4
• Descriptor: Protein arginine N-methyltransferase 5, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• Functional Keywords: tim-barrel, rossmann fold, beta-barrel, symmetric arginine dimethylase, sam binding, symmetric dimethylation, nucleus, transferase
• Biological source: Caenorhabditis elegans
• Total number of polymer chains: 2
• Total formula weight: 171858.74

Authors

Sun, L.,Wang, M.,Lv, Z.,Yang, N.,Liu, Y.,Bao, S.,Gong, W.,Xu, R.M. (deposition date: 2011-10-20, release date: 2011-12-14, Last modification date: 2011-12-28)

• Primary citation: Sun, L.,Wang, M.,Lv, Z.,Yang, N.,Liu, Y.,Bao, S.,Gong, W.,Xu, R.M.; Structural insights into protein arginine symmetric dimethylation by PRMT5; Proc.Natl.Acad.Sci.USA, 108:20538-20543, 2011; PubMed: 22143770; DOI: 10.1073/pnas.1106946108

Experimental method

X-RAY DIFFRACTION (3 Å)