3U9U
Crystal Structure of Extracellular Domain of Human ErbB4/Her4 in complex with the Fab fragment of mAb1479
Summary for 3U9U
Entry DOI | 10.2210/pdb3u9u/pdb |
Descriptor | Fab Heavy Chain, Fab Light Chain, Receptor tyrosine-protein kinase erbB-4 (3 entities in total) |
Functional Keywords | cell surface receptor, transferase, tyrosine kinase receptor |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell membrane ; Single-pass type I membrane protein . ERBB4 intracellular domain: Nucleus : Q15303 |
Total number of polymer chains | 6 |
Total formula weight | 236537.40 |
Authors | Hollmen, M.,Liu, P.,Wildiers, H.,Reinvall, I.,Vandorpe, T.,Smeets, A.,Deraedt, K.,Vahlberg, T.,Joensuu, H.,Leahy, D.J.,Schoffski, P.,Elenius, K. (deposition date: 2011-10-19, release date: 2012-10-31, Last modification date: 2023-09-13) |
Primary citation | Hollmen, M.,Liu, P.,Kurppa, K.,Wildiers, H.,Reinvall, I.,Vandorpe, T.,Smeets, A.,Deraedt, K.,Vahlberg, T.,Joensuu, H.,Leahy, D.J.,Schoffski, P.,Elenius, K. Proteolytic processing of ErbB4 in breast cancer. Plos One, 7:e39413-e39413, 2012 Cited by PubMed: 22761786DOI: 10.1371/journal.pone.0039413 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.42 Å) |
Structure validation
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