3U7G

Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)

Summary for 3U7G

• Entry DOI: 10.2210/pdb3u7g/pdb
• Related: 1YJ5 3U7E 3U7f 3U7h
• Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... (6 entities in total)
• Functional Keywords: protein-dna complex, had family, pnkp, dna repair, phosphatase, hydrolase, transferase-dna complex, transferase/dna
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus : Q9JLV6
• Total number of polymer chains: 2
• Total formula weight: 44134.07

Authors

Coquelle, N.,Havali, Z.,Bernstein, N.,Green, R.,Glover, J.N.M. (deposition date: 2011-10-13, release date: 2011-12-14, Last modification date: 2017-11-08)

• Primary citation: Coquelle, N.,Havali-Shahriari, Z.,Bernstein, N.,Green, R.,Glover, J.N.; Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.; Proc.Natl.Acad.Sci.USA, 108:21022-21027, 2011; PubMed: 22171004; DOI: 10.1073/pnas.1112036108

Experimental method

X-RAY DIFFRACTION (2.1 Å)