3U74

Crystal structure of stabilized human uPAR mutant

Summary for 3U74

Entry DOI	10.2210/pdb3u74/pdb
Related	2FAT 3BT1 3BT2
Descriptor	Urokinase plasminogen activator surface receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	glycosylation, hydrolase receptor
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor. Isoform 2: Secreted (Probable): Q03405
Total number of polymer chains	1
Total formula weight	32100.99
Authors	Huang, M.D.,Xu, X.,Yuan, C. (deposition date: 2011-10-13, release date: 2012-04-18, Last modification date: 2023-09-13)
Primary citation	Xu, X.,Gardsvoll, H.,Yuan, C.,Lin, L.,Ploug, M.,Huang, M. Crystal structure of the urokinase receptor in a ligand-free form. J.Mol.Biol., 416:629-641, 2012 Cited by PubMed: 22285761 DOI: 10.1016/j.jmb.2011.12.058 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.39 Å)

Structure validation