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3U4U

Casein kinase 2 in complex with AZ-Inhibitor

Summary for 3U4U
Entry DOI10.2210/pdb3u4u/pdb
DescriptorCasein kinase II subunit alpha, 3-{5-(acetylamino)-3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-1H-indol-1-yl}propanoic acid, CHLORIDE ION, ... (4 entities in total)
Functional Keywordskinase, transferase, inhibitor binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight40357.41
Authors
Larsen, N.A.,Dowling, J. (deposition date: 2011-10-10, release date: 2012-08-22, Last modification date: 2024-02-28)
Primary citationDowling, J.E.,Chuaqui, C.,Pontz, T.W.,Lyne, P.D.,Larsen, N.A.,Block, M.H.,Chen, H.,Su, N.,Wu, A.,Russell, D.,Pollard, H.,Lee, J.W.,Peng, B.,Thakur, K.,Ye, Q.,Zhang, T.,Brassil, P.,Racicot, V.,Bao, L.,Denz, C.R.,Cooke, E.
Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization.
ACS Med Chem Lett, 3:278-283, 2012
Cited by
PubMed: 24900464
DOI: 10.1021/ml200257n
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

221051

건을2024-06-12부터공개중

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