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3U4E

Crystal Structure of PG9 Fab in Complex with V1V2 Region from HIV-1 strain CAP45

Summary for 3U4E
Entry DOI10.2210/pdb3u4e/pdb
Related3U2S 3U46 3U4B
DescriptorV1V2 region of HIV-1 on 1FD6 scaffold, PG9 Heavy Chain, PG9 Light Chain, ... (9 entities in total)
Functional Keywordsneutralizing antibodies, long cdrh3, hiv-1, immune system
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains6
Total formula weight132968.08
Authors
Gorman, J.,McLellan, J.,Pancera, M.,Kwong, P.D. (deposition date: 2011-10-07, release date: 2011-11-30, Last modification date: 2023-12-06)
Primary citationMcLellan, J.S.,Pancera, M.,Carrico, C.,Gorman, J.,Julien, J.P.,Khayat, R.,Louder, R.,Pejchal, R.,Sastry, M.,Dai, K.,O'Dell, S.,Patel, N.,Shahzad-Ul-Hussan, S.,Yang, Y.,Zhang, B.,Zhou, T.,Zhu, J.,Boyington, J.C.,Chuang, G.Y.,Diwanji, D.,Georgiev, I.,Do Kwon, Y.,Lee, D.,Louder, M.K.,Moquin, S.,Schmidt, S.D.,Yang, Z.Y.,Bonsignori, M.,Crump, J.A.,Kapiga, S.H.,Sam, N.E.,Haynes, B.F.,Burton, D.R.,Koff, W.C.,Walker, L.M.,Phogat, S.,Wyatt, R.,Orwenyo, J.,Wang, L.X.,Arthos, J.,Bewley, C.A.,Mascola, J.R.,Nabel, G.J.,Schief, W.R.,Ward, A.B.,Wilson, I.A.,Kwong, P.D.
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480:336-343, 2011
Cited by
PubMed: 22113616
DOI: 10.1038/nature10696
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.185 Å)
Structure validation

217705

數據於2024-03-27公開中

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