3U1J
Aprotinin bound to Dengue virus protease
3U1J の概要
エントリーDOI | 10.2210/pdb3u1j/pdb |
関連するPDBエントリー | 3U1I |
分子名称 | Serine protease subunit NS2B, Serine protease NS3, Pancreatic trypsin inhibitor, ... (4 entities in total) |
機能のキーワード | serine protease, bovine pancreatic trypsin inhibitor, er membrane, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Dengue virus 3 (DENV-3) 詳細 |
細胞内の位置 | Capsid protein C: Virion (Potential). Peptide pr: Secreted (By similarity). Small envelope protein M: Virion membrane; Multi-pass membrane protein (By similarity). Envelope protein E: Virion membrane; Multi- pass membrane protein (By similarity). Non-structural protein 1: Secreted. Non-structural protein 2A-alpha: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Non-structural protein 2A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): Q5UB51 Q5UB51 Secreted: P00974 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 32272.02 |
構造登録者 | |
主引用文献 | Noble, C.G.,Seh, C.C.,Chao, A.T.,Shi, P.Y. Ligand-bound structures of the dengue virus protease reveal the active conformation J.Virol., 86:438-446, 2012 Cited by PubMed: 22031935DOI: 10.1128/JVI.06225-11 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.8 Å) |
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