3U17

Structure of BasE N-terminal domain from Acinetobacter baumannii bound to 6-(p-benzoyl)phenyl-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

3U17 の概要

• エントリーDOI: 10.2210/pdb3u17/pdb
• 関連するPDBエントリー: 3O82 3O83 3O84 3U16
• 分子名称: Peptide arylation enzyme, 6-(4-benzoylphenyl)-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: anl superfamily, adenylating enzyme, 2, 3-dihydroxybenzoate:aryl carrier protein ligase, basf, ligase
• 由来する生物種: Acinetobacter baumannii
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 123122.33

構造登録者

Gulick, A.M.,Drake, E.J.,Aldrich, C.C.,Neres, J. (登録日: 2011-09-29, 公開日: 2012-10-03, 最終更新日: 2023-09-13)

• 主引用文献: Neres, J.,Engelhart, C.A.,Drake, E.J.,Wilson, D.J.,Fu, P.,Boshoff, H.I.,Barry 3rd, C.E.,Gulick, A.M.,Aldrich, C.C.; Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.; J.Med.Chem., 56:2385-2405, 2013; PubMed: 23437866; DOI: 10.1021/jm301709s

実験手法

X-RAY DIFFRACTION (2.1 Å)