3TYU

Crystal Structure of Dihydropteroate synthetase with Product1

Summary for 3TYU

• Entry DOI: 10.2210/pdb3tyu/pdb
• Related: 3TYZ 3TZF 3TZN
• Descriptor: 7,8-dihydropteroate synthase, PTEROIC ACID (3 entities in total)
• Functional Keywords: paba inhibitor, dihydropteroate analog, tim barrel, transferase
• Biological source: Yersinia pestis
• Total number of polymer chains: 2
• Total formula weight: 61260.02

Authors

Yun, M.K. (deposition date: 2011-09-26, release date: 2012-03-14, Last modification date: 2023-09-13)

• Primary citation: Yun, M.K.,Wu, Y.,Li, Z.,Zhao, Y.,Waddell, M.B.,Ferreira, A.M.,Lee, R.E.,Bashford, D.,White, S.W.; Catalysis and sulfa drug resistance in dihydropteroate synthase.; Science, 335:1110-1114, 2012; PubMed: 22383850; DOI: 10.1126/science.1214641

Experimental method

X-RAY DIFFRACTION (2.7 Å)