3TWM

Crystal structure of Arabidopsis thaliana FPG

3TWM の概要

• エントリーDOI: 10.2210/pdb3twm/pdb
• 関連するPDBエントリー: 3TWK 3TWL
• 分子名称: Formamidopyrimidine-DNA glycosylase 1, 5'-D(*AP*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*AP*GP*AP*CP*GP*TP*GP*GP*AP*CP*GP*C)-3', ... (4 entities in total)
• 機能のキーワード: helix two turns helix, zinc-less finger, hydrolase, dna damage, dna repair, dna-binding, glycosidase, lyase, multifunctional enzyme, dna containing stable analog of abasic site, tetrahydro furan, hydrolase-dna complex, hydrolase/dna
• 由来する生物種: Arabidopsis thaliana (mouse-ear cress, thale-cress); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 88751.97

構造登録者

Duclos, S.,Aller, P.,Wallace, S.S.,Doublie, S. (登録日: 2011-09-22, 公開日: 2012-07-25, 最終更新日: 2023-09-13)

• 主引用文献: Duclos, S.,Aller, P.,Jaruga, P.,Dizdaroglu, M.,Wallace, S.S.,Doublie, S.; Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine.; Dna Repair, 11:714-725, 2012; PubMed: 22789755; DOI: 10.1016/j.dnarep.2012.06.004

実験手法

X-RAY DIFFRACTION (2.8 Å)