3TSZ
crystal structure of PDZ3-SH3-GUK core module from human ZO-1 in complex with 12mer peptide from human JAM-A cytoplasmic tail
Summary for 3TSZ
Entry DOI | 10.2210/pdb3tsz/pdb |
Related | 3TSV 3TSW |
Descriptor | Tight junction protein ZO-1, Junctional adhesion molecule A (3 entities in total) |
Functional Keywords | pdz3-sh3-guk, scaffolding, jam, tight junction, cell adhesion |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q07157 Cell junction, tight junction: Q9Y624 |
Total number of polymer chains | 2 |
Total formula weight | 46033.41 |
Authors | |
Primary citation | Nomme, J.,Fanning, A.S.,Caffrey, M.,Lye, M.F.,Anderson, J.M.,Lavie, A. The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1. J.Biol.Chem., 286:43352-43360, 2011 Cited by PubMed: 22030391DOI: 10.1074/jbc.M111.304089 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.502 Å) |
Structure validation
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