3TMJ

Joint X-ray/neutron structure of human carbonic anhydrase II at pH 7.8

3TMJ の概要

• エントリーDOI: 10.2210/pdb3tmj/pdb
• 分子名称: Carbonic anhydrase 2, ZINC ION (3 entities in total)
• 機能のキーワード: h/d exchanged, joint neutron/x-ray refinement, lyase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29136.19

構造登録者

Fisher, Z. (登録日: 2011-08-31, 公開日: 2011-11-09, 最終更新日: 2023-09-13)

• 主引用文献: Fisher, Z.,Kovalevsky, A.Y.,Mustyakimov, M.,Silverman, D.N.,McKenna, R.,Langan, P.; Neutron Structure of Human Carbonic Anhydrase II: A Hydrogen-Bonded Water Network "Switch" Is Observed between pH 7.8 and 10.0.; Biochemistry, 50:9421-9423, 2011; PubMed: 21988105; DOI: 10.1021/bi201487b

実験手法

NEUTRON DIFFRACTION (2 Å)
X-RAY DIFFRACTION