3TH3

Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+

3TH3 の概要

• エントリーDOI: 10.2210/pdb3th3/pdb
• 関連するPDBエントリー: 2A2Q 3TH2 3TH4
• 関連するBIRD辞書のPRD_ID: PRD_000287
• 分子名称: Coagulation factor VII light chain, Coagulation factor VII heavy chain, Tissue factor, ... (9 entities in total)
• 機能のキーワード: hydrolase, blood clotting, serine protease, blood coagulation, soluble tissue factor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 68854.04

構造登録者

Vadivel, K.,Agah, S.,Cascio, D.,Padmanabhan, K.,Bajaj, S.P. (登録日: 2011-08-18, 公開日: 2012-08-22, 最終更新日: 2023-12-06)

• 主引用文献: Vadivel, K.,Agah, S.,Messer, A.,Cascio, D.,Bajaj, M.S.,Krishnaswamy, S.,Esmon, C.T.,Padmanabhan, K.,Bajaj, S.P.; Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+; To be Published,

実験手法

X-RAY DIFFRACTION (2.7 Å)