3TDD

Crystal structure of yeast CP in complex with Belactosin C

3TDD の概要

• エントリーDOI: 10.2210/pdb3tdd/pdb
• 関連するPDBエントリー: 1RYP 3E47
• 分子名称: Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (16 entities in total)
• 機能のキーワード: ubiquitin, inhibitor, proteasome, drug development, primed substrate binding channel, beta-sandwich flanked by alpha-helices, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• 細胞内の位置: Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451
• タンパク質・核酸の鎖数: 28
• 化学式量合計: 705473.70

構造登録者

Korotkov, V.S.,Ludwig, A.,Larionov, O.V.,Lygin, A.V.,Groll, M.,de Meijere, A. (登録日: 2011-08-10, 公開日: 2011-10-12, 最終更新日: 2023-09-13)

• 主引用文献: Korotkov, V.S.,Ludwig, A.,Larionov, O.V.,Lygin, A.V.,Groll, M.,de Meijere, A.; Synthesis and biological activity of optimized belactosin C congeners.; Org.Biomol.Chem., 9:7791-7798, 2011; PubMed: 21946808; DOI: 10.1039/c1ob05661a

実験手法

X-RAY DIFFRACTION (2.7 Å)