3TAF

5-fluorocytosine paired with ddGMP in RB69 gp43

Summary for 3TAF

• Entry DOI: 10.2210/pdb3taf/pdb
• Related: 3TAB 3TAE 3TAG
• Descriptor: DNA-directed DNA polymerase, DNA (5'-D(*CP*CP*(C37)P*GP*GP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*CP*CP*G)-3'), ... (5 entities in total)
• Functional Keywords: transferase-dna complex, transferase/dna
• Biological source: Escherichia phage RB69; More
• Total number of polymer chains: 12
• Total formula weight: 461088.67

Authors

Zahn, K.E. (deposition date: 2011-08-04, release date: 2011-11-09, Last modification date: 2024-02-28)

• Primary citation: Zahn, K.E.,Averill, A.,Wallace, S.S.,Doublie, S.; The miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site.; Biochemistry, 50:10350-10358, 2011; PubMed: 22026756; DOI: 10.1021/bi201219s

Experimental method

X-RAY DIFFRACTION (3 Å)