3T8X

Crystal structure of human CD1b in complex with synthetic antigenic diacylsulfoglycolipid SGL12 and endogenous spacer

Summary for 3T8X

• Entry DOI: 10.2210/pdb3t8x/pdb
• Related: 2H26
• Descriptor: T-cell surface glycoprotein CD1b, GLYCEROL, Beta-2-microglobulin, ... (11 entities in total)
• Functional Keywords: endogenous spacer ligand, mycobacterial diacylsulfoglycolipid, mhc, glycoprotein, immune system, immunoglobulin domain/mhc i, antigen presentation, glycolipid antigen binding, glycosylation, cell membrane
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 96734.55

Authors

Garcia-Alles, L.F.,Maveyraud, L.,Mourey, L.,Julien, S. (deposition date: 2011-08-02, release date: 2011-10-26, Last modification date: 2024-10-30)

• Primary citation: Garcia-Alles, L.F.,Collmann, A.,Versluis, C.,Lindner, B.,Guiard, J.,Maveyraud, L.,Huc, E.,Im, J.S.,Sansano, S.,Brando, T.,Julien, S.,Prandi, J.,Gilleron, M.,Porcelli, S.A.,de la Salle, H.,Heck, A.J.R.,Mori, L.,Puzo, G.,Mourey, L.,De Libero, G.; Structural reorganization of the human CD1b Antigen-binding groove for presentation of mycobacterial sulfoglycolipids; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)