3T8I

Structural analysis of thermostable S. solfataricus purine-specific nucleoside hydrolase

Summary for 3T8I

Entry DOI	10.2210/pdb3t8i/pdb
Related	1Q8F 2MAS 3G5I 3T8J
Descriptor	Purine nucleosidase, (IunH-2), CALCIUM ION, GLYCEROL, ... (6 entities in total)
Functional Keywords	purine nucleoside hydrolase, thermostable protein, open (alpha, beta) structure, rossmann fold, nh-fold, nucleoside hydrolase, nucleotide metabolism, n-glycosidase, hydrolase
Biological source	Sulfolobus solfataricus
Total number of polymer chains	4
Total formula weight	139190.37
Authors	Minici, C.,Cacciapuoti, G.,De Leo, E.,Porcelli, M.,Degano, M. (deposition date: 2011-08-01, release date: 2012-05-16, Last modification date: 2023-09-13)
Primary citation	Minici, C.,Cacciapuoti, G.,De Leo, E.,Porcelli, M.,Degano, M. New Determinants in the Catalytic Mechanism of Nucleoside Hydrolases from the Structures of Two Isozymes from Sulfolobus solfataricus. Biochemistry, 51:4590-4599, 2012 Cited by PubMed: 22551416 DOI: 10.1021/bi300209g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation