3T3E

Glycogen phosphorylase b in complex with GlcClU

3T3E の概要

• エントリーDOI: 10.2210/pdb3t3e/pdb
• 関連するPDBエントリー: 3SYM 3SYR 3T3D 3T3G 3T3H 3T3I
• 分子名称: Glycogen phosphorylase, muscle form, 5-chloro-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione (3 entities in total)
• 機能のキーワード: a+b protein, transferase, muscle, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 97827.99

構造登録者

Kantsadi, A.L.,Skamnaki, V.T.,Leonidas, D.D. (登録日: 2011-07-25, 公開日: 2012-02-15, 最終更新日: 2023-12-06)

• 主引用文献: Kantsadi, A.L.,Hayes, J.M.,Manta, S.,Skamnaki, V.T.,Kiritsis, C.,Psarra, A.M.,Koutsogiannis, Z.,Dimopoulou, A.,Theofanous, S.,Nikoleousakos, N.,Zoumpoulakis, P.,Kontou, M.,Papadopoulos, G.,Zographos, S.E.,Komiotis, D.,Leonidas, D.D.; The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase b; Chemmedchem, 7:722-732, 2012; PubMed: 22267166; DOI: 10.1002/cmdc.201100533

実験手法

X-RAY DIFFRACTION (2.15 Å)