3SUU

Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 in complex with Gal-PUGNAc

Summary for 3SUU

• Entry DOI: 10.2210/pdb3suu/pdb
• Related: 3SUR 3SUS 3SUT 3SUV 3SUW
• Descriptor: Beta-hexosaminidase, SULFATE ION, [(Z)-[(3R,4R,5R,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-ylidene]amino] N-phenylcarbamate, ... (4 entities in total)
• Functional Keywords: structural genomics, riken structural genomics/proteomics initiative, rsgi, tim barrel, carbohydrate/sugar binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Paenibacillus
• Total number of polymer chains: 1
• Total formula weight: 58015.50

Authors

Sumida, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2011-07-11, release date: 2012-06-06, Last modification date: 2023-11-01)

• Primary citation: Sumida, T.,Stubbs, K.A.,Ito, M.,Yokoyama, S.; Gaining insight into the inhibition of glycoside hydrolase family 20 exo-beta-N-acetylhexosaminidases using a structural approach; Org.Biomol.Chem., 10:2607-2612, 2012; PubMed: 22367352; DOI: 10.1039/c2ob06636j

Experimental method

X-RAY DIFFRACTION (1.6 Å)