3STG

Crystal structure of A58P, DEL(N59), and loop 7 truncated mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

Summary for 3STG

Entry DOI	10.2210/pdb3stg/pdb
Related	3STC 3STE 3STF
Descriptor	2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION (3 entities in total)
Functional Keywords	manno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8 kdops, kdo8ps, tim barrel, biosynthesis, transferase, lyase, lipopolysaccharide biosynthesis
Biological source	Neisseria meningitidis
Cellular location	Cytoplasm (By similarity): Q9JZ55
Total number of polymer chains	4
Total formula weight	118138.48
Authors	Allison, T.M.,Jameson, G.B.,Parker, E.J. (deposition date: 2011-07-09, release date: 2011-11-23, Last modification date: 2023-11-01)
Primary citation	Allison, T.M.,Hutton, R.D.,Jiao, W.,Gloyne, B.J.,Nimmo, E.B.,Jameson, G.B.,Parker, E.J. An Extended (beta)7(alpha)7 Substrate-Binding Loop Is Essential for Efficient Catalysis by 3-Deoxy-D-manno-Octulosonate 8-Phosphate Synthase Biochemistry, 50:9318-9327, 2011 Cited by PubMed: 21942786 DOI: 10.1021/bi201231e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation