3SR2

Crystal Structure of Human XLF-XRCC4 Complex

3SR2 の概要

• エントリーDOI: 10.2210/pdb3sr2/pdb
• 分子名称: DNA repair protein XRCC4, Non-homologous end-joining factor 1 (2 entities in total)
• 機能のキーワード: xrcc4, xlf, nhej, dna repair, dna, dna ligases, dna-binding proteins, dimerization, humans, protein structure, quaternary, complex, non-homologous end joining (nhej), dna ligase iv, ku, xlf-xrcc4, protein dna-interaction, dna binding protein-protein binding complex, dna binding protein/protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: Q13426 Q9H9Q4
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 168501.06

構造登録者

Hammel, M.,Classen, S.,Tainer, J.A. (登録日: 2011-07-06, 公開日: 2011-07-20, 最終更新日: 2023-09-13)

• 主引用文献: Hammel, M.,Rey, M.,Yu, Y.,Mani, R.S.,Classen, S.,Liu, M.,Pique, M.E.,Fang, S.,Mahaney, B.L.,Weinfeld, M.,Schriemer, D.C.,Lees-Miller, S.P.,Tainer, J.A.; XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair.; J.Biol.Chem., 286:32638-32650, 2011; PubMed: 21775435; DOI: 10.1074/jbc.M111.272641

実験手法

X-RAY DIFFRACTION (3.9708 Å)