3SQV

Crystal Structure of E. coli O157:H7 E3 ubiquitin ligase, NleL, with a human E2, UbcH7

3SQV の概要

• エントリーDOI: 10.2210/pdb3sqv/pdb
• 分子名称: secreted effector protein, Ubiquitin-conjugating enzyme E2 L3, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: effector protein, pentapeptide, hect domain, hect e3 ubiquitin ligase, e2 ubiquitin conjugating enzyme, protein-protein complex, ubiquitin transfer, ubiquitin, ubiquitination, ligase-signaling protein complex, ligase/signaling protein
• 由来する生物種: Escherichia coli; 詳細
• 細胞内の位置: Nucleus: P68036
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 176608.76

構造登録者

Lin, D.Y.,Chen, J. (登録日: 2011-07-06, 公開日: 2012-01-25, 最終更新日: 2023-09-13)

• 主引用文献: Lin, D.Y.,Diao, J.,Chen, J.; Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions.; Proc.Natl.Acad.Sci.USA, 109:1925-1930, 2012; PubMed: 22308380; DOI: 10.1073/pnas.1115025109

実験手法

X-RAY DIFFRACTION (3.3 Å)