3SMQ

Crystal structure of protein arginine methyltransferase 3

Summary for 3SMQ

Entry DOI	10.2210/pdb3smq/pdb
Descriptor	Protein arginine N-methyltransferase 3, 1-(1,2,3-benzothiadiazol-6-yl)-3-[2-(cyclohex-1-en-1-yl)ethyl]urea, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	structural genomics, structural genomics consortium, sgc, prmt3, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: O60678
Total number of polymer chains	1
Total formula weight	38619.76
Authors	Dobrovetsky, E.,Dong, A.,Walker, J.R.,Siarheyeva, A.,Senisterra, G.,Wasney, G.A.,Smil, D.,Bolshan, Y.,Nguyen, K.T.,Allali-Hassani, A.,Hajian, T.,Poda, G.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Al-Awar, R.,Brown, P.J.,Schapira, M.,Arrowsmith, C.H.,Vedadi, M.,Structural Genomics Consortium (SGC) (deposition date: 2011-06-28, release date: 2011-08-31, Last modification date: 2023-09-13)
Primary citation	Siarheyeva, A.,Senisterra, G.,Allali-Hassani, A.,Dong, A.,Dobrovetsky, E.,Wasney, G.A.,Chau, I.,Marcellus, R.,Hajian, T.,Liu, F.,Korboukh, I.,Smil, D.,Bolshan, Y.,Min, J.,Wu, H.,Zeng, H.,Loppnau, P.,Poda, G.,Griffin, C.,Aman, A.,Brown, P.J.,Jin, J.,Al-Awar, R.,Arrowsmith, C.H.,Schapira, M.,Vedadi, M. An allosteric inhibitor of protein arginine methyltransferase 3. Structure, 20:1425-1435, 2012 Cited by PubMed: 22795084 DOI: 10.1016/j.str.2012.06.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation