3SKJ
Structural And Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody
Summary for 3SKJ
Entry DOI | 10.2210/pdb3skj/pdb |
Descriptor | Antibody, light chain, Antibody, heavy chain, Ephrin type-A receptor 2, ... (4 entities in total) |
Functional Keywords | fab, receptor, ig fold, ephrin receptor, antibody, antigen, extra-cellular, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Single- pass type I membrane protein : P29317 |
Total number of polymer chains | 6 |
Total formula weight | 142941.75 |
Authors | Oganesyan, V.Y.,Wu, H.,Dall'Acqua, W.F. (deposition date: 2011-06-22, release date: 2011-08-31, Last modification date: 2017-05-31) |
Primary citation | Peng, L.,Oganesyan, V.,Damschroder, M.M.,Wu, H.,Dall'Acqua, W.F. Structural and functional characterization of an agonistic anti-human EphA2 monoclonal antibody. J.Mol.Biol., 413:390-405, 2011 Cited by PubMed: 21867711DOI: 10.1016/j.jmb.2011.08.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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