3SJU
Hedamycin Polyketide Ketoreductase bound to NADPH
Summary for 3SJU
Entry DOI | 10.2210/pdb3sju/pdb |
Descriptor | Keto reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | short-chain dehydrogenase, reductase, oxidoreductase, rossmann fold, type ii polyketide ketoreductase |
Biological source | Streptomyces griseoruber |
Total number of polymer chains | 2 |
Total formula weight | 59409.66 |
Authors | Javidpour, P.,Tsai, S.-C. (deposition date: 2011-06-21, release date: 2011-09-07, Last modification date: 2024-02-28) |
Primary citation | Javidpour, P.,Das, A.,Khosla, C.,Tsai, S.C. Structural and Biochemical Studies of the Hedamycin Type II Polyketide Ketoreductase (HedKR): Molecular Basis of Stereo- and Regiospecificities. Biochemistry, 50:7426-7439, 2011 Cited by PubMed: 21776967DOI: 10.1021/bi2006866 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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