3SI3

Human Thrombin In Complex With UBTHR103

3SI3 の概要

• エントリーDOI: 10.2210/pdb3si3/pdb
• 関連するPDBエントリー: 3P17 3QTO 3QTV 3QWC 3QX5 3RLW
• 関連するBIRD辞書のPRD_ID: PRD_000790
• 分子名称: Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ... (9 entities in total)
• 機能のキーワード: serine protease, kringle, hydrolase, blood coagulation, blood clotting, convertion of fibrinogen to fibrin, cleavage on pairs of basic residues, blood clotting inhibitor, thrombin inhibitor, glycosylation, blood, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36346.12

構造登録者

Biela, A.,Heine, A.,Klebe, G. (登録日: 2011-06-17, 公開日: 2012-06-20, 最終更新日: 2023-12-06)

• 主引用文献: Biela, A.,Khayat, M.,Tan, H.,Kong, J.,Heine, A.,Hangauer, D.,Klebe, G.; Impact of ligand and protein desolvation on ligand binding to the S1 pocket of thrombin; J.Mol.Biol., 418:350-366, 2012; PubMed: 22366545; DOI: 10.1016/j.jmb.2012.01.054

実験手法

X-RAY DIFFRACTION (1.55 Å)