3SG8

Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type IVa Tobramycin Complex

3SG8 の概要

• エントリーDOI: 10.2210/pdb3sg8/pdb
• 分子名称: APH(2'')-Id, TOBRAMYCIN, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: antibiotic resistance enzyme, transferase, aminoglycoside, phosphorylation, transferase-antibiotic complex, transferase/antibiotic
• 由来する生物種: Enterococcus casseliflavus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72687.30

構造登録者

Shi, K.,Houston, D.R.,Berghuis, A.M. (登録日: 2011-06-14, 公開日: 2011-06-29, 最終更新日: 2024-02-28)

• 主引用文献: Shi, K.,Houston, D.R.,Berghuis, A.M.; Crystal Structures of Antibiotic-Bound Complexes of Aminoglycoside 2''-Phosphotransferase IVa Highlight the Diversity in Substrate Binding Modes among Aminoglycoside Kinases.; Biochemistry, 50:6237-6244, 2011; PubMed: 21678960; DOI: 10.1021/bi200747f

実験手法

X-RAY DIFFRACTION (1.8 Å)