3SEZ

Crystal structure of C176A mutant of glutamine-dependent NAD+ synthetase from M. tuberculosis in complex with ATP and NaAD+

3SEZ の概要

• エントリーDOI: 10.2210/pdb3sez/pdb
• 関連するPDBエントリー: 3DLA 3SDB 3SEQ
• 分子名称: Glutamine-dependent NAD(+) synthetase, ADENOSINE-5'-TRIPHOSPHATE, NICOTINIC ACID ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: glutamine-amidotransferase, glutaminase, glutamine-dependent nad+ synthetase, ligase, ammonia tunneling, atp binding, nad, nucleotide binding
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 303983.80

構造登録者

Chuenchor, W.,Gerratana, B. (登録日: 2011-06-11, 公開日: 2012-04-11, 最終更新日: 2023-09-13)

• 主引用文献: Chuenchor, W.,Doukov, T.I.,Resto, M.,Chang, A.,Gerratana, B.; Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase.; Biochem.J., 443:417-426, 2012; PubMed: 22280445; DOI: 10.1042/BJ20112210

実験手法

X-RAY DIFFRACTION (2.6529 Å)