3SD0

Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice

3SD0 の概要

• エントリーDOI: 10.2210/pdb3sd0/pdb
• 分子名称: Glycogen synthase kinase-3 beta, 3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P49841
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 81114.72

構造登録者

Mesecar, A.M.,Walters, R.L. (登録日: 2011-06-08, 公開日: 2011-08-03, 最終更新日: 2024-02-28)

• 主引用文献: Mesecar, A.M.,Walters, R.L.; Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice; To be Published,

実験手法

X-RAY DIFFRACTION (2.7 Å)