3S8K

Crystal structure of a papaya latex serine protease inhibitor (PPI) at 1.7A resolution

Summary for 3S8K

• Entry DOI: 10.2210/pdb3s8k/pdb
• Related: 3S8J
• Descriptor: Latex serine proteinase inhibitor, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ... (7 entities in total)
• Functional Keywords: kunitz-sti fold, protease inhibitor, hydrolase inhibitor
• Biological source: Carica papaya (mamon)
• Total number of polymer chains: 2
• Total formula weight: 43719.69

Authors

Garcia-Pino, A. (deposition date: 2011-05-29, release date: 2011-11-02, Last modification date: 2020-07-29)

• Primary citation: Azarkan, M.,Martinez-Rodriguez, S.,Buts, L.,Baeyens-Volant, D.,Garcia-Pino, A.; The plasticity of the beta-Trefoil fold constitutes an evolutionary platform for protease inhibition; J.Biol.Chem., 286:43726-43734, 2011; PubMed: 22027836; DOI: 10.1074/jbc.M111.291310

Experimental method

X-RAY DIFFRACTION (1.7 Å)