3S7D
Structural Basis of Substrate Methylation and Inhibition of SMYD2
Summary for 3S7D
Entry DOI | 10.2210/pdb3s7d/pdb |
Related | 3S7B 3S7F 3S7J |
Descriptor | N-lysine methyltransferase SMYD2, Monomethylated p53 peptide, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total) |
Functional Keywords | methyltransferase, p53, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol (By similarity): Q9NRG4 |
Total number of polymer chains | 2 |
Total formula weight | 52074.72 |
Authors | Ferguson, A.D. (deposition date: 2011-05-26, release date: 2011-08-10, Last modification date: 2011-09-21) |
Primary citation | Ferguson, A.D.,Larsen, N.A.,Howard, T.,Pollard, H.,Green, I.,Grande, C.,Cheung, T.,Garcia-Arenas, R.,Cowen, S.,Wu, J.,Godin, R.,Chen, H.,Keen, N. Structural Basis of Substrate Methylation and Inhibition of SMYD2. Structure, 19:1262-1273, 2011 Cited by PubMed: 21782458DOI: 10.1016/j.str.2011.06.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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