3S79
Human placental aromatase cytochrome P450 (CYP19A1) refined at 2.75 angstrom
Summary for 3S79
Entry DOI | 10.2210/pdb3s79/pdb |
Related | 3S7S |
Descriptor | Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE, ... (5 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Peripheral membrane protein: P11511 |
Total number of polymer chains | 1 |
Total formula weight | 59142.67 |
Authors | Ghosh, D. (deposition date: 2011-05-26, release date: 2012-06-06, Last modification date: 2023-09-13) |
Primary citation | Ghosh, D.,Lo, J.,Morton, D.,Valette, D.,Xi, J.,Griswold, J.,Hubbell, S.,Egbuta, C.,Jiang, W.,An, J.,Davies, H.M. Novel aromatase inhibitors by structure-guided design. J.Med.Chem., 55:8464-8476, 2012 Cited by PubMed: 22951074DOI: 10.1021/jm300930n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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