3S5J

2.0A Crystal structure of human phosphoribosyl pyrophosphate synthetase 1

Summary for 3S5J

• Entry DOI: 10.2210/pdb3s5j/pdb
• Descriptor: Ribose-phosphate pyrophosphokinase 1, SULFATE ION (3 entities in total)
• Functional Keywords: nucleotide synthesis, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 72477.13

Authors

Chen, P.,Teng, M.,Li, X. (deposition date: 2011-05-23, release date: 2012-05-23, Last modification date: 2023-11-01)

• Primary citation: Chen, P.,Liu, Z.,Wang, X.,Peng, J.,Sun, Q.,Li, J.,Wang, M.,Niu, L.,Zhang, Z.,Cai, G.,Teng, M.,Li, X.; Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations; Plos One, 10:e0120304-e0120304, 2015; PubMed: 25781187; DOI: 10.1371/journal.pone.0120304

Experimental method

X-RAY DIFFRACTION (2.02 Å)