3S4L

The CRISPR-associated Cas3 HD domain protein MJ0384 from Methanocaldococcus jannaschii

Replaces:  3M5F

Summary for 3S4L

• Entry DOI: 10.2210/pdb3s4l/pdb
• Descriptor: CAS3 Metal dependent phosphohydrolase, CALCIUM ION (3 entities in total)
• Functional Keywords: immune system, hd-motif, structural genomics, psi-biology, midwest center for structural genomics, mcsg, nuclease, hydrolase
• Biological source: Methanocaldococcus jannaschii
• Total number of polymer chains: 1
• Total formula weight: 28532.87

Authors

Petit, P.,Brown, G.,Yakunin, A.,Edwards, A.,Joachimiak, A.,Savchenko, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2011-05-19, release date: 2011-06-22, Last modification date: 2024-02-28)

• Primary citation: Beloglazova, N.,Petit, P.,Flick, R.,Brown, G.,Savchenko, A.,Yakunin, A.F.; Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference.; Embo J., 30:4616-4627, 2011; PubMed: 22009198; DOI: 10.1038/emboj.2011.377

Experimental method

X-RAY DIFFRACTION (2.3 Å)