3S3K

Crystal structure of the catalytic domain of PTP10D from Drosophila melanogaster with a small molecular inhibitor para-NitroCatechol Sulphate

Summary for 3S3K

Entry DOI	10.2210/pdb3s3k/pdb
Related	3S3E 3S3F 3S3H
Descriptor	Tyrosine-protein phosphatase 10D, N,4-DIHYDROXY-N-OXO-3-(SULFOOXY)BENZENAMINIUM (3 entities in total)
Functional Keywords	differentiation, neurogenesis, signal transduction, developmental protein, hydrolase, protein phosphatase, protein tyrosine phosphatase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Drosophila melanogaster (Fruit fly)
Cellular location	Membrane; Single-pass type I membrane protein: P35992
Total number of polymer chains	2
Total formula weight	72126.44
Authors	Madan, L.L.,Gopal, B. (deposition date: 2011-05-18, release date: 2011-11-02, Last modification date: 2023-11-01)
Primary citation	Madan, L.L.,Gopal, B. Conformational basis for substrate recruitment in protein tyrosine phosphatase 10D Biochemistry, 50:10114-10125, 2011 Cited by PubMed: 22007620 DOI: 10.1021/bi201092q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation