3S3K

Crystal structure of the catalytic domain of PTP10D from Drosophila melanogaster with a small molecular inhibitor para-NitroCatechol Sulphate

3S3K の概要

• エントリーDOI: 10.2210/pdb3s3k/pdb
• 関連するPDBエントリー: 3S3E 3S3F 3S3H
• 分子名称: Tyrosine-protein phosphatase 10D, N,4-DIHYDROXY-N-OXO-3-(SULFOOXY)BENZENAMINIUM (3 entities in total)
• 機能のキーワード: differentiation, neurogenesis, signal transduction, developmental protein, hydrolase, protein phosphatase, protein tyrosine phosphatase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P35992
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72126.44

構造登録者

Madan, L.L.,Gopal, B. (登録日: 2011-05-18, 公開日: 2011-11-02, 最終更新日: 2023-11-01)

• 主引用文献: Madan, L.L.,Gopal, B.; Conformational basis for substrate recruitment in protein tyrosine phosphatase 10D; Biochemistry, 50:10114-10125, 2011; PubMed: 22007620; DOI: 10.1021/bi201092q

実験手法

X-RAY DIFFRACTION (3.2 Å)