3RZ2

Crystal of Prl-1 complexed with peptide

Summary for 3RZ2

Entry DOI	10.2210/pdb3rz2/pdb
Descriptor	Protein tyrosine phosphatase type IVA 1, Prl-1 (PTP4A1) (3 entities in total)
Functional Keywords	tyrosine phosphatase, prl-1, dual specific phosphatase, complexed with peptide, hydrolase
Biological source	Rattus norvegicus (rat)
Cellular location	Cell membrane : Q78EG7
Total number of polymer chains	4
Total formula weight	46061.29
Authors	Zhang, Z.-Y.,Liu, D.,Bai, Y. (deposition date: 2011-05-11, release date: 2011-10-26, Last modification date: 2014-10-29)
Primary citation	Bai, Y.,Luo, Y.,Liu, S.,Zhang, L.,Shen, K.,Dong, Y.,Walls, C.D.,Quilliam, L.A.,Wells, C.D.,Cao, Y.,Zhang, Z.Y. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. J.Biol.Chem., 286:42316-42324, 2011 Cited by PubMed: 22009749 DOI: 10.1074/jbc.M111.286302 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation