3RZ2
Crystal of Prl-1 complexed with peptide
Summary for 3RZ2
Entry DOI | 10.2210/pdb3rz2/pdb |
Descriptor | Protein tyrosine phosphatase type IVA 1, Prl-1 (PTP4A1) (3 entities in total) |
Functional Keywords | tyrosine phosphatase, prl-1, dual specific phosphatase, complexed with peptide, hydrolase |
Biological source | Rattus norvegicus (rat) |
Cellular location | Cell membrane : Q78EG7 |
Total number of polymer chains | 4 |
Total formula weight | 46061.29 |
Authors | Zhang, Z.-Y.,Liu, D.,Bai, Y. (deposition date: 2011-05-11, release date: 2011-10-26, Last modification date: 2014-10-29) |
Primary citation | Bai, Y.,Luo, Y.,Liu, S.,Zhang, L.,Shen, K.,Dong, Y.,Walls, C.D.,Quilliam, L.A.,Wells, C.D.,Cao, Y.,Zhang, Z.Y. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. J.Biol.Chem., 286:42316-42324, 2011 Cited by PubMed: 22009749DOI: 10.1074/jbc.M111.286302 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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