3RYB

Lactococcal OppA complexed with SLSQSLSQS

3RYB の概要

• エントリーDOI: 10.2210/pdb3ryb/pdb
• 関連するPDBエントリー: 3DRF 3DRG 3DRH 3DRI 3DRJ 3DRK 3FTO 3RYA
• 分子名称: Oligopeptide-binding protein oppA, Oligopeptide (3 entities in total)
• 機能のキーワード: substrate-binding protein, peptide binding, membrane anchored, peptide binding protein
• 由来する生物種: Lactococcus lactis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 66080.75

構造登録者

Berntsson, R.P.-A.,Thunnissen, A.-M.W.H.,Poolman, B.,Slotboom, D.-J. (登録日: 2011-05-11, 公開日: 2011-06-29, 最終更新日: 2023-09-13)

主引用文献

Berntsson, R.P.,Thunnissen, A.M.,Poolman, B.,Slotboom, D.J.
Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA.
J.Bacteriol., 193:4254-4256, 2011

PubMed Abstract: Lactococcal oligopeptide-binding protein A (OppA) binds peptides with widely varied lengths and sequences. We previously hypothesized that a hydrophobic pocket in OppA preferentially binds a hydrophobic peptide side chain and thus determines its binding register. Two crystal structures of OppA with different nonapeptides now indeed show binding in different registers.

PubMed: 21665971
DOI: 10.1128/JB.00447-11

実験手法

X-RAY DIFFRACTION (1.5 Å)