3RT4

Structural Basis of Recognition of Pathogen-associated Molecular Patterns and Inhibition of Proinflammatory Cytokines by Camel Peptidoglycan Recognition Protein

Replaces:  3MU9

Summary for 3RT4

• Entry DOI: 10.2210/pdb3rt4/pdb
• Descriptor: Peptidoglycan recognition protein 1, (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, L(+)-TARTARIC ACID, ... (4 entities in total)
• Functional Keywords: immune response, secreted, antimicrobial, pgrp, peptidoglycan binding, immune system
• Biological source: Camelus dromedarius (camel,dromedaries,dromedary,one-humped camel)
• Total number of polymer chains: 4
• Total formula weight: 76907.78

Authors

Sharma, P.,Dube, D.,Singh, A.,Mishra, B.,Singh, N.,Sinha, M.,Dey, S.,Kaur, P.,Mitra, D.K.,Sharma, S.,Singh, T.P. (deposition date: 2011-05-03, release date: 2011-06-15, Last modification date: 2023-11-01)

• Primary citation: Sharma, P.,Dube, D.,Singh, A.,Mishra, B.,Singh, N.,Sinha, M.,Dey, S.,Kaur, P.,Mitra, D.K.,Sharma, S.,Singh, T.P.; Structural Basis of Recognition of Pathogen-associated Molecular Patterns and Inhibition of Proinflammatory Cytokines by Camel Peptidoglycan Recognition Protein.; J.Biol.Chem., 286:16208-16217, 2011; PubMed: 21454594; DOI: 10.1074/jbc.M111.228163

Experimental method

X-RAY DIFFRACTION (1.7 Å)