3RSC

Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form

3RSC の概要

• エントリーDOI: 10.2210/pdb3rsc/pdb
• 関連するPDBエントリー: 3IAA
• 分子名称: CalG2, THYMIDINE-5'-DIPHOSPHATE, Calicheamicin T0, ... (5 entities in total)
• 機能のキーワード: tdp, enediyne, structural genomics, psi-2, protein structure initiative, center for eukaryotic structural genomics, cesg, glycosyltransferase, transferase-antibiotic complex, enzyme discovery for natural product biosynthesis, natpro, transferase/antibiotic
• 由来する生物種: Micromonospora echinospora
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 94010.23

構造登録者

Chang, A.,Helmich, K.E.,Singh, S.,Bingman, C.A.,Thorson, J.S.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (登録日: 2011-05-02, 公開日: 2011-08-10, 最終更新日: 2017-11-08)

• 主引用文献: Chang, A.,Singh, S.,Helmich, K.E.,Goff, R.D.,Bingman, C.A.,Thorson, J.S.,Phillips, G.N.; Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.; Proc.Natl.Acad.Sci.USA, 108:17649-17654, 2011; PubMed: 21987796; DOI: 10.1073/pnas.1108484108

実験手法

X-RAY DIFFRACTION (2.19 Å)