3RJ5
Structure of alcohol dehydrogenase from Drosophila lebanonesis T114V mutant complexed with NAD+
Summary for 3RJ5
Entry DOI | 10.2210/pdb3rj5/pdb |
Related | 1a4u 1b15 |
Descriptor | Alcohol dehydrogenase, ACETIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | short-chain dehydrogenases/reductases, oxidoreductase, detoxification, nad metabolism |
Biological source | Scaptodrosophila lebanonensis (Fruit fly) |
Total number of polymer chains | 2 |
Total formula weight | 56367.48 |
Authors | Morgunova, E.,Wuxiuer, Y.,Cols, N.,Popov, A.,Sylte, I.,Karshikoff, A.,Gonzales-Duarte, R.,Ladenstein, R.,Winberg, J.O. (deposition date: 2011-04-15, release date: 2012-05-02, Last modification date: 2023-09-13) |
Primary citation | Wuxiuer, Y.,Morgunova, E.,Cols, N.,Popov, A.,Karshikoff, A.,Sylte, I.,Gonzalez-Duarte, R.,Ladenstein, R.,Winberg, J.O. An intact eight-membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activity. Febs J., 279:2940-2956, 2012 Cited by PubMed: 22741949DOI: 10.1111/j.1742-4658.2012.08675.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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