3RIS

Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme

Summary for 3RIS

Entry DOI	10.2210/pdb3ris/pdb
Related	3IHR
Descriptor	Ubiquitin carboxyl-terminal hydrolase isozyme L5, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	alpha-beta-alpha fold, cysteine protease, thiol hydrolase, deubiquitinating enzyme, ubiquitin hydrolase, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9Y5K5
Total number of polymer chains	4
Total formula weight	110849.23
Authors	Das, C.,Permaul, M.,Maiti, T.K. (deposition date: 2011-04-14, release date: 2011-11-09, Last modification date: 2024-02-28)
Primary citation	Maiti, T.K.,Permaul, M.,Boudreaux, D.A.,Mahanic, C.,Mauney, S.,Das, C. Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme. Febs J., 278:4917-4926, 2011 Cited by PubMed: 21995438 DOI: 10.1111/j.1742-4658.2011.08393.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.398 Å)

Structure validation