3RBE

Dpo4 extension ternary complex with 3'-terminal primer t base opposite the 3-methylcytosine (m3c) lesion

3RBE の概要

• エントリーDOI: 10.2210/pdb3rbe/pdb
• 関連するPDBエントリー: 3RAQ 3RAX 3RB0 3RB4 3RB6 3RBD
• 分子名称: DNA polymerase IV, DNA (5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DT))-3'), DNA (5'-D(*C*CP*TP*AP*AP*CP*(ME6)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ... (6 entities in total)
• 機能のキーワード: dna damage, dna repair, dna replication, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, transferase, transferase-dna complex, lesion bypass, dna polymerase, y-family polymerase, dntp-binding, 3-methylcytosine, transferase/dna
• 由来する生物種: Sulfolobus solfataricus; 詳細
• 細胞内の位置: Cytoplasm (Probable): Q97W02
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 99154.69

構造登録者

Rechkoblit, O.,Patel, D.J. (登録日: 2011-03-29, 公開日: 2011-06-15, 最終更新日: 2023-09-13)

• 主引用文献: Rechkoblit, O.,Delaney, J.C.,Essigmann, J.M.,Patel, D.J.; Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.; Structure, 19:821-832, 2011; PubMed: 21645853; DOI: 10.1016/j.str.2011.03.020

実験手法

X-RAY DIFFRACTION (2.8 Å)